Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771240 | 0.93 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL11770433 | 0.84 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL11774987 | 0.81 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL11774864 | 0.80 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL11768536 | 0.79 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL28495995 | 0.77 | ALDH1A1 (0.67) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL4842294 | 0.74 | POLB (0.71) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL7769541 | 0.74 | SMN1; SMN2 (0.60) | RAB9ANPC1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL823582 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2AMAPTMEN1POLB | |
| SCHEMBL11770861 | 0.72 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953595-A | Substituted benzoic acid hypolipemic agents | PFIZER INC. (US) | 1976-04-27 | — | — | US | disclosed |