SCHEMBL117748

SCHEMBL117748

Nc1cccc(Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29876609 1.00
Bromide SCHEMBL27585534 0.97
Cyanide SCHEMBL28325242 0.93 NOS2 (0.44)
SCHEMBL1256448 0.83 ALDH1A1 (0.42)
Dimethylformamide SCHEMBL28080709 0.82 NOS3 (0.41)
SCHEMBL58195 0.78
SCHEMBL64599 0.78
Water SCHEMBL9078960 0.76
Ammonia Solution, Strong SCHEMBL10709860 0.76 NOS2 (0.60)
Hydrochloric Acid SCHEMBL8446392 0.76 NOS2 (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085157-A1 Metal-backboned polymer and preparation method and use thereof FUDAN UNIVERSITY (CN) 2026-03-26 US claimed
CN-119390645-A Dehalogenation method for reducing N heteroaryl halide by using hydrosilane 浙江科技大学 2025-02-07 CN claimed
WO-2024093176-A1 HIGH POLYMER CONTAINING METAL ELEMENT AS MAIN CHAIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF 复旦大学 2024-05-10 WO claimed
CN-116354900-B Chlorothiazole compound containing maleic acid structure, and preparation method and application thereof 中国农业大学 2024-03-12 CN claimed
CN-115894958-B Metal main chain polymer with precise length and synthesis method and application thereof 复旦大学 2023-11-07 CN claimed
CN-115746309-B Polymer with main chain as metal element, and preparation method and application thereof 复旦大学 2023-08-29 CN claimed
CN-116354900-A Chlorothiazole compound containing maleic acid structure, and preparation method and application thereof 中国农业大学 2023-06-30 CN claimed
EP-3867238-B1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS ARRAY BIOPHARMA INC (US) 2023-06-07 EP claimed
CN-115894958-A Metal main chain polymer with accurate length and synthesis method and application thereof 复旦大学 2023-04-04 CN claimed
CN-115746309-A Macromolecule with main chain of metal element and preparation method and application thereof 复旦大学 2023-03-07 CN claimed
EP-1987003-A1 PYRIDINE-2-CARBOXAMIDE DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2008-11-05 EP claimed
WO-2008048991-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2008-04-24 WO claimed
EP-1844044-A1 THIAZOLE-4-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS F.HOFFMANN-LA ROCHE AG (CH) 2007-10-17 EP claimed
WO-2007093542-A1 PYRIDINE-2-CARBOXAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2007-08-23 WO claimed
US-20070197553-A1 4-Aryl-pyridine-2-carboxyamide derivatives HOFFMANN-LA ROCHE INC. 2007-08-23 US claimed
WO-2006074884-A1 THIAZOLE-4-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS F.HOFFMANN-LA ROCHE AG (CH) 2006-07-20 WO claimed
US-20060160857-A1 Thiazole-4-carboxyamide derivatives HOFFMANN-LA ROCHE INC. 2006-07-20 US claimed
EP-1230235-A1 COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES New Pharma Research Sweden AB (SE) 2002-08-14 EP claimed
WO-2001036408-A1 COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES NEW PHARMA RESEARCH SWEDEN AB (SE) 2001-05-25 WO claimed
EP-0267675-A2 Modified conjugated diene polymer and process for production thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-05-18 EP claimed