Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | MAOA | P21397 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | AHR | P35869 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibenzofuran SCHEMBL9868133 | 0.97 | MAPT (0.68) | MAPTMAOAKDM4EALDH1A1HPGD | |
| Dibenzofuran SCHEMBL29635704 | 0.97 | MAPT (0.68) | MAPTMAOAKDM4EALDH1A1HPGD | |
| Dibenzofuran SCHEMBL8207 | 0.97 | MAPT (0.68) | MAPTMAOAKDM4EALDH1A1HPGD | |
| Dibenzofuran SCHEMBL11775205 | 0.93 | MAPT (0.65) | MAPTMAOAKDM4EALDH1A1HPGD | |
| Dibenzofuran SCHEMBL21436811 | 0.93 | MAPT (0.65) | MAPTMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL24307195 | 0.93 | MAPT (0.65) | MAPTMAOAKDM4EALDH1A1HPGD | |
| Dibenzofuran SCHEMBL7262648 | 0.93 | MAPT (0.65) | MAPTMAOAKDM4EALDH1A1HPGD | |
| Dibenzofuran SCHEMBL2278940 | 0.93 | MAPT (0.65) | MAPTMAOAKDM4EALDH1A1HPGD | |
| Dibenzofuran SCHEMBL9932653 | 0.93 | MAOA (0.65) | MAPTMAOAKDM4EALDH1A1HPGD | |
| Dibenzofuran SCHEMBL9932651 | 0.93 | KDM4E (0.65) | MAPTMAOAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035428-A | DEHYDRATION, DEHYDRAGENATION | MONSANTO COMPANY (US) | 1977-07-12 | — | — | US | claimed |