Dibenzofuran

Dibenzofuran

SCHEMBL9932653

[B].c1ccc2c(c1)oc1ccccc12

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 6/20 0.65
▸ MAPT P10636 5/20 0.65
▸ KDM4E B2RXH2 4/20 0.65
▸ ALDH1A1 P00352 4/20 0.65
▸ HPGD P15428 3/20 0.65
▸ SMN1; SMN2 Q16637 2/20 0.65
▸ GLA P06280 1/20 0.65
▸ CYP3A4 P08684 1/20 0.65
▸ PGAM1 P18669 1/20 0.65
▸ CASP1 P29466 1/20 0.65
▸ CASP7 P55210 1/20 0.65
▸ HSD17B10 Q99714 1/20 0.65
▸ AHR P35869 3/20 0.58
▸ MEN1 O00255 3/20 0.58
▸ KMT2A Q03164 3/20 0.58
▸ NPC1 O15118 2/20 0.58
▸ RAB9A P51151 1/20 0.58
▸ NQO1 P15559 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzofuran SCHEMBL9868133 0.97 MAPT (0.68) MAOAMAPTKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL29635704 0.97 MAPT (0.68) MAOAMAPTKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL8207 0.97 MAPT (0.68) MAOAMAPTKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL11775205 0.93 MAPT (0.65) MAOAMAPTKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL21436811 0.93 MAPT (0.65) MAOAMAPTKDM4EALDH1A1HPGD
SCHEMBL24307195 0.93 MAPT (0.65) MAOAMAPTKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL11564675 0.93 MAPT (0.65) MAOAMAPTKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL2278940 0.93 MAPT (0.65) MAOAMAPTKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL11775200 0.93 MAPT (0.65) MAOAMAPTKDM4EALDH1A1HPGD
Dibenzofuran SCHEMBL9932651 0.93 KDM4E (0.65) MAOAMAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664263-B2 Stilbene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-04 — — US disclosed
US-8580980-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-12 — — US disclosed
US-20120184755-A1 Stilbene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-07-19 — — US disclosed
US-20120157694-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184755-A1 Stilbene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device ESR1, ESR2, NR2E3 MAOA 3285/4885MAPT 2632/4885KDM4E 1773/4885
US-20120157694-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device CYP1A1, CRY1, AHR MAOA 1756/4885MAPT 3454/4885KDM4E 2381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback