Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721162 | 0.87 | KDM4E (0.51) | KDM4EPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL1945357 | 0.84 | KDM4E (0.42) | KDM4EPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL16047514 | 0.84 | KCNH2 (0.42) | CA12CA1CA2CA9CA14 | |
| SCHEMBL16035755 | 0.83 | KDM4E (0.40) | KDM4EPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL719539 | 0.83 | CA12 (0.47) | KDM4EPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL721132 | 0.83 | KDM4E (0.53) | KDM4EPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL720191 | 0.82 | KDM4E (0.41) | KDM4EPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL16036947 | 0.81 | KDM4E (0.39) | KDM4EPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL719484 | 0.81 | RAB9A (0.41) | KDM4EPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL718383 | 0.81 | LMNA (0.41) | KDM4EPKMSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102458118-A | Method for controlling weed plants | SYNGENTA LTD | 2012-05-16 | — | — | CN | disclosed |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| EP-2424367-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | Syngenta Limited (GB) | 2012-03-07 | — | — | EP | disclosed |
| US-20110136666-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110136666-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110136666-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| EP-2303015-A2 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010125332-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA LIMITED (GB) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010125332-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA LIMITED (GB) | 2010-11-04 | — | — | WO | disclosed |
| WO-2009138712-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009138712-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136666-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CYP2W1 | KDM4E 2495/4885PKM 2922/4885SMN1; SMN2 2548/4885 |
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | TYMS, DHFR, UNG | KDM4E 2202/4885PKM 2730/4885SMN1; SMN2 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.