Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651755 | 0.87 | AHR (0.37) | MCOLN3TSHRPTGES2TTRACLY | |
| SCHEMBL4630192 | 0.85 | PTPRC (0.43) | TSHRTTRPGAM1HSD11B1CA1 | |
| SCHEMBL562742 | 0.82 | TSHR (0.52) | MCOLN3TSHRPTGES2TTRPGR | |
| SCHEMBL458284 | 0.82 | SMN1; SMN2 (0.48) | TSHRTTRPGAM1CA1CA2 | |
| SCHEMBL13278151 | 0.80 | TSHR (0.50) | MCOLN3TSHRPTGES2TTRPGR | |
| Hydrochloric Acid SCHEMBL942823 | 0.80 | TSHR (0.50) | MCOLN3TSHRPTGES2TTRPGR | |
| SCHEMBL680068 | 0.80 | MCOLN3 (0.41) | MCOLN3TSHRPTGES2PGRACLY | |
| SCHEMBL28837581 | 0.80 | SMN1; SMN2 (0.46) | TSHRTTRPGAM1CA1CA2 | |
| SCHEMBL27922124 | 0.78 | STAT3 (0.47) | TSHRPTGES2TTRCA1CA2 | |
| SCHEMBL9056122 | 0.78 | ADORA2A (0.41) | MCOLN3TSHRTTRPGAM1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048315-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |