SCHEMBL4630192

SCHEMBL4630192

O=S(=O)(O)c1ccccc1-c1ccccc1-c1ccccc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.43
HSD11B1 P28845 3/20 0.41
CYP2A6 P11509 1/20 0.40
HSP90AA1 P07900 2/20 0.39
HSP90AB1 P08238 2/20 0.39
ALDH1A1 P00352 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PGAM1 P18669 1/20 0.39
DPP4 P27487 1/20 0.38
NAT1 P18440 1/20 0.38
MYC P01106 1/20 0.38
NAMPT P43490 1/20 0.38
IDO1 P14902 1/20 0.37
DNMT1 P26358 1/20 0.37
DNMT3L Q9UJW3 1/20 0.37
DNMT3A Q9Y6K1 1/20 0.37
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458284 0.85 SMN1; SMN2 (0.48) PTPRCL3MBTL1PGAM1MYCTSHR
SCHEMBL11775615 0.85 MCOLN3 (0.42) HSD11B1PGAM1MYCTSHRCA1
SCHEMBL28837581 0.83 SMN1; SMN2 (0.46) PTPRCL3MBTL1PGAM1MYCTSHR
SCHEMBL769320 0.82 S100A4 (0.46) HSD11B1HSP90AA1HSP90AB1ALDH1A1PGAM1
SCHEMBL29365345 0.82 S100A4 (0.46) HSD11B1HSP90AA1HSP90AB1ALDH1A1PGAM1
SCHEMBL14956040 0.81 PTPRC (0.47) PTPRCHSD11B1CYP2A6HSP90AA1HSP90AB1
SCHEMBL9056122 0.81 ADORA2A (0.41) PTPRCHSD11B1CYP2A6HSP90AA1HSP90AB1
SCHEMBL30454753 0.81 HSD11B1 (0.47) HSD11B1ALDH1A1L3MBTL1MYCTSHR
SCHEMBL50612 0.81 HSD11B1 (0.47) HSD11B1ALDH1A1L3MBTL1MYCTSHR
SCHEMBL28407818 0.80 CA2 (0.47) PTPRCHSD11B1DPP4CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1920255-A1 COMPLEX FORMATION METHOD AND SEPARATION METHOD Wako Pure Chemical Industries, Ltd. (JP) 2008-05-14 EP disclosed
WO-2007027495-A1 COMPLEX FORMATION METHOD AND SEPARATION METHOD WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 2007-03-08 WO disclosed