SCHEMBL458284

SCHEMBL458284

O=S(=O)(O)c1ccccc1-c1ccccc1S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
TSHR P16473 1/20 0.48
PGAM1 P18669 1/20 0.47
MYC P01106 1/20 0.47
TTR P02766 2/20 0.45
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
CDC25B P30305 1/20 0.43
APAF1 O14727 2/20 0.42
TDP2 O95551 2/20 0.42
PLCG1 P19174 2/20 0.41
MAPT P10636 2/20 0.41
MAOA P21397 2/20 0.41
POLB P06746 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CES2 O00748 1/20 0.41
TERT O14746 1/20 0.41
NPC1 O15118 1/20 0.41
PLIN1 O60240 1/20 0.41
S1PR4 O95977 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28837581 0.97 SMN1; SMN2 (0.46) SMN1; SMN2TSHRPGAM1MYCTTR
SCHEMBL29700277 0.89 PGAM1 (0.44) SMN1; SMN2TSHRPGAM1MYCTTR
SCHEMBL6155652 0.89 PGAM1 (0.44) SMN1; SMN2TSHRPGAM1MYCTTR
SCHEMBL27914240 0.87 PGAM1 (0.43) SMN1; SMN2TSHRPGAM1MYCTTR
SCHEMBL8949303 0.87 PTGS2 (0.47) SMN1; SMN2TSHRPGAM1MYCTTR
SCHEMBL776011 0.87 NPSR1 (0.43) SMN1; SMN2TSHRPGAM1MYCTTR
SCHEMBL2593808 0.87 PGAM1 (0.40) SMN1; SMN2TSHRPGAM1MYCTTR
SCHEMBL3886759 0.87 MYC (0.47) SMN1; SMN2TSHRPGAM1MYCTTR
SCHEMBL232659 0.85 CASP1 (0.47) SMN1; SMN2TSHRPGAM1MYCTTR
SCHEMBL29743050 0.85 CASP1 (0.47) SMN1; SMN2TSHRPGAM1MYCTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3813786-A1 COMPOSITIONS COMPRISING SILICON DIOXIDE-BASED PARTICLES INCLUDING ONE OR MORE AGENTS Colabs International Corporation (US) 2021-05-05 EP claimed
EP-3180373-B1 BIOMATERIAL WITH REDUCED INFLAMMATORY RESPONSE GOVERNING COUNCIL UNIV TORONTO (CA) 2021-04-07 EP claimed
US-10629953-B2 Lithium ion secondary battery ENVISION AESC JAPAN LTD. (JP) 2020-04-21 US claimed
EP-2638544-B1 PHOTOPOLYMER FORMULATION FOR PRODUCING HOLOGRAPHIC MEDIA HAVING HIGHLY CROSS-LINKED MATRIX POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2018-12-26 EP claimed
EP-3413981-A1 COMPOSITIONS CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN ACTIVE AGENT Colabs International Corporation (US) 2018-12-19 EP claimed
WO-2017139701-A1 COMPOSITIONS CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN ACTIVE AGENT CoLabs International Corporation (US) 2017-08-17 WO claimed
EP-3180373-A1 BIOMATERIAL WITH REDUCED INFLAMMATORY RESPONSE The Governing Council of the University of Toronto (CA) 2017-06-21 EP claimed
CN-106356561-A Overcharge-preventing electrolyte and lithium ion battery 宁德时代新能源科技股份有限公司 2017-01-25 CN claimed
CN-105111979-B Environment-friendly type antibiotic fire-retardant TPE carpet back-adhesive powder and preparation method thereof 安徽雄亚塑胶科技有限公司 2016-10-05 CN claimed
US-20160237073-A1 Novel Polymorphs and Salts GLAXO GROUP LTD (GB) 2016-08-18 US claimed
WO-2006005444-A1 CATIONIC METAL COMPLEXES FOR USE AS LIGHT-ABSORBING COMPOUNDS IN THE INFORMATION LAYER OF OPTICAL DATA CARRIERS LANXESS DEUTSCHLAND GMBH (DE) 2006-01-19 WO claimed
US-6767481-B2 AT LEAST ONE REDUCIBLE AND AT LEAST ONE OXIDIZABLE SUBSTANCE OX2 AND RED1, RESPECTIVELY, WHICH ARE LINKED TO ONE ANOTHER VIA A BRIDGE BAYER AKTIENGESELLSCHAFT (DE) 2004-07-27 US claimed
US-20020197486-A1 Electrochromic system with coupled RED-OX system and special anions BERNETH HORST (DE) 2002-12-26 US claimed
US-6417951-B1 ELECTROLYTIC CELLS BAYER AKTIENGESELLSCHAFT (DE) 2002-07-09 US claimed
EP-1015524-A1 ELECTROCHROMIC SYSTEM WITH COUPLED RED-OX SYSTEM AND SPECIAL ANIONS BAYER AG (DE) 2000-07-05 EP claimed
WO-1999009111-A1 ELECTROCHROMIC SYSTEM WITH COUPLED RED-OX SYSTEM AND SPECIAL ANIONS BAYER AKTIENGESELLSCHAFT (DE) 1999-02-25 WO claimed
WO-1988009783-A1 POLYMERIC ULTRAVIOLET LIGHT ABSORBERS BIOPOLYMERS LIMITED (AU) 1988-12-15 WO claimed
EP-0032072-B1 SURFACTANT COMPOSITIONS USEFUL IN ENHANCED OIL RECOVERY PROCESSES THE DOW CHEMICAL COMPANY (US) 1983-05-18 EP claimed
EP-0001629-B1 WATER-SOLUBLE, FIBRE-REACTIVE, GREEN AZO-PHTHALOCYANINE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-08-12 EP claimed
US-4038031-A REACTION WITH DIAZONIUM COMPOUND MILES LABORATORIES, INC. (US) 1977-07-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160237073-A1 Novel Polymorphs and Salts PRKDC, PRKACA, MAP3K20 SMN1; SMN2 4783/4885TSHR 3265/4885PGAM1 1518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.