Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771125 | 0.95 | TSHR (0.47) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL9670556 | 0.92 | CYP1A2 (0.48) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL11773016 | 0.88 | L3MBTL1 (0.46) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL31141913 | 0.76 | TSHR (0.47) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL6273604 | 0.73 | TSHR (0.60) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL13342911 | 0.72 | LMNA (0.55) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| Trimethylammonium SCHEMBL11775959 | 0.72 | TSHR (0.48) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL11854026 | 0.71 | TSHR (0.58) | TSHRHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL28806667 | 0.71 | PPARG (0.45) | TSHRCYP1A2CYP2C9GAASCN4A | |
| SCHEMBL7932790 | 0.70 | TSHR (0.57) | TSHRHTR2AHTR2CHTR2BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933851-A | Preparation of aromatic 2-imino-1,3-dithietanes | AMERICAN CYANAMID COMPANY (US) | 1976-01-20 | — | — | US | disclosed |