Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777337 | 0.88 | GPBAR1 (0.37) | ADORA2AADORA1ALDH1A1CYP3A4ADCY10 | |
| SCHEMBL11820800 | 0.86 | HSD11B1 (0.38) | ADORA2AADORA1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11808484 | 0.84 | HSD11B1 (0.40) | MEN1KMT2AGAAP2RX7 | |
| SCHEMBL11774332 | 0.82 | NR1H2 (0.40) | ADORA2AADORA1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11773018 | 0.81 | CYP1A2 (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2APLA2G1B | |
| SCHEMBL27828729 | 0.73 | GAA (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL11772838 | 0.72 | MEN1 (0.46) | ALDH1A1MEN1KMT2AHSD17B10CYP3A4 | |
| SCHEMBL13180099 | 0.72 | HSP90AA1 (0.48) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL11775029 | 0.71 | MAPT (0.41) | ALDH1A1MEN1KMT2ACYP2C9GAA | |
| SCHEMBL11772878 | 0.71 | P2RX7 (0.36) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992400-A | 1-(α-Phenyl-o-tolyl)imidazoles | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |