Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820800 | 0.86 | HSD11B1 (0.38) | HSD11B1P2RX7MAPTTP53MEN1 | |
| SCHEMBL11777337 | 0.85 | GPBAR1 (0.37) | P2RX7MAPTPTGDR2 | |
| SCHEMBL11774993 | 0.84 | PTGDR2 (0.41) | SMOPTGDR2NPY5R | |
| SCHEMBL11776643 | 0.84 | ADORA2A (0.38) | P2RX7MEN1KMT2AGAA | |
| SCHEMBL11774188 | 0.83 | P2RX7 (0.41) | HSD11B1NR2E1P2RX7CSNK1DSMO | |
| SCHEMBL11773018 | 0.79 | CYP1A2 (0.39) | MAPTMEN1KMT2A | |
| SCHEMBL11818051 | 0.76 | RORB (0.46) | HSD11B1MAPTMEN1KMT2AGAA | |
| SCHEMBL11772878 | 0.72 | P2RX7 (0.36) | HSD11B1P2RX7MAPTTP53MEN1 | |
| SCHEMBL11775812 | 0.72 | HPGD (0.40) | NR2E1MAPTTP53GAA | |
| SCHEMBL11772838 | 0.72 | MEN1 (0.46) | MEN1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |