Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12871986 | 0.87 | PTGES (0.59) | PTGESPTGS2 | |
| SCHEMBL7605967 | 0.85 | PTGES (0.65) | PTGESPTGS2 | |
| SCHEMBL1178895 | 0.84 | PTGES (0.64) | PTGESPTGS2 | |
| SCHEMBL1178393 | 0.84 | PTGES (0.63) | PTGESPTGS2 | |
| SCHEMBL17857968 | 0.83 | PTGS2 (1.00) | PTGESPTGS2 | |
| SCHEMBL17847173 | 0.83 | PTGS2 (1.00) | PTGESPTGS2 | |
| SCHEMBL1178402 | 0.83 | PTGS2 (0.67) | PTGESPTGS2 | |
| SCHEMBL13660762 | 0.83 | PTGES (0.62) | PTGESPTGS2 | |
| SCHEMBL17846825 | 0.82 | PTGES (0.71) | PTGESPTGS2 | |
| SCHEMBL1177876 | 0.82 | PTGES (0.66) | PTGESPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987256-B2 | Oxo-heterocyclic substituted carboxylic acid derivatives and the use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| US-20110034450-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIEGESELLSCHAFT (DE) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034450-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF | OTC, PC, HCAR2 | PTGES 224/4885PTGS2 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.