Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19699467 | 0.85 | LMNA (0.63) | TRPV1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL4026073 | 0.82 | TRPV1 (1.00) | TRPV1KMT2AMEN1MAPK1HTT | |
| SCHEMBL8513508 | 0.81 | TRPV1 (0.65) | TRPV1KMT2AMEN1MAPK1HTT | |
| SCHEMBL15478234 | 0.81 | TRPV1 (0.65) | TRPV1KMT2AMEN1MAPK1HTT | |
| SCHEMBL19976895 | 0.81 | MEN1 (0.63) | TRPV1LMNAKMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL116218 | 0.81 | TRPV1 (0.64) | TRPV1KMT2AMEN1MAPK1HTT | |
| SCHEMBL5660097 | 0.80 | TRPV1 (0.71) | TRPV1 | |
| SCHEMBL116573 | 0.80 | TRPV1 (0.63) | TRPV1KMT2AMEN1MAPK1HTT | |
| SCHEMBL30114438 | 0.79 | TRPV1 (0.64) | TRPV1LMNAKMT2AMEN1MAPK1 | |
| SCHEMBL4023786 | 0.79 | TRPV1 (0.64) | TRPV1LMNAKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424857-A1 | DUAL-ACTION INHIBITORS AND METHODS OF USING SAME | Aerie Pharmaceuticals, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |