Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 8/20 | 0.75 |
| ▸ | CTSL | P07711 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CHRND | Q07001 | 6/20 | 0.60 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.60 |
| ▸ | CHRNG | P07510 | 2/20 | 0.60 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.60 |
| ▸ | PLG | P00747 | 1/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10543878 | 0.95 | GRIA1 (0.71) | GRIA1CTSLL3MBTL1CHRNDCHRNA1 | |
| SCHEMBL10543883 | 0.95 | GRIA1 (0.71) | GRIA1CTSLL3MBTL1CHRNDCHRNA1 | |
| SCHEMBL11776777 | 0.91 | L3MBTL1 (0.76) | GRIA1CTSLL3MBTL1CHRNDCHRNA1 | |
| SCHEMBL4651392 | 0.87 | GRIA1 (0.73) | GRIA1CTSLL3MBTL1CHRNDCHRNA1 | |
| SCHEMBL11775228 | 0.86 | GRIA1 (0.57) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL11772567 | 0.86 | CTSL (0.77) | GRIA1CTSLL3MBTL1 | |
| SCHEMBL22372487 | 0.84 | CHRND (0.59) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL11778440 | 0.84 | CHRND (0.57) | GRIA1CTSLL3MBTL1CHRNDCHRNA1 | |
| SCHEMBL506060 | 0.83 | NAAA (0.65) | GRIA1L3MBTL1 | |
| SCHEMBL506059 | 0.83 | NAAA (0.65) | GRIA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |