Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 8/20 | 0.57 |
| ▸ | CHRND | Q07001 | 5/20 | 0.57 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.57 |
| ▸ | CHRNG | P07510 | 1/20 | 0.57 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777557 | 0.96 | CHRND (0.56) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL11796137 | 0.86 | GRIA1 (0.75) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10543883 | 0.81 | GRIA1 (0.71) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10543878 | 0.81 | GRIA1 (0.71) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL22372487 | 0.79 | CHRND (0.59) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL16993998 | 0.79 | PYGL (0.50) | — | |
| SCHEMBL16999320 | 0.79 | PYGL (0.50) | — | |
| SCHEMBL11779711 | 0.78 | ACE (0.46) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL11775760 | 0.77 | PLG (0.46) | PLGPLAUPRSS1PRSS2PRSS3 | |
| SCHEMBL11776777 | 0.76 | L3MBTL1 (0.76) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |