Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777604 | 1.00 | CA2 (0.43) | CA2CA1CA9CA12KDM4E | |
| SCHEMBL11779282 | 0.91 | CA2 (0.38) | CA2CA1CA9CA12KDM4E | |
| SCHEMBL11779276 | 0.91 | CA2 (0.38) | CA2CA1CA9CA12KDM4E | |
| SCHEMBL11782595 | 0.89 | MEN1 (0.43) | KDM4ELMNAALDH1A1HPGDTSHR | |
| SCHEMBL11782600 | 0.89 | MEN1 (0.43) | KDM4ELMNAALDH1A1HPGDTSHR | |
| SCHEMBL11783802 | 0.84 | CISD1 (0.47) | CA2CA1CA9CA12KDM4E | |
| SCHEMBL11780993 | 0.84 | CA2 (0.56) | CA2CA1CA9CA12KDM4E | |
| SCHEMBL11799181 | 0.83 | CA2 (0.38) | CA2CA1CA9CA12KDM4E | |
| SCHEMBL11802068 | 0.83 | CA2 (0.56) | CA2CA1CA9CA12KDM4E | |
| SCHEMBL11802057 | 0.83 | CA2 (0.56) | CA2CA1CA9CA12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |