Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782595 | 1.00 | MEN1 (0.43) | MEN1KMT2AGAAGFERPTGER4 | |
| SCHEMBL11777604 | 0.89 | CA2 (0.43) | MEN1KMT2AGAAGFERMAPT | |
| SCHEMBL11777610 | 0.89 | CA2 (0.43) | MEN1KMT2AGAAGFERMAPT | |
| SCHEMBL11781708 | 0.84 | MEN1 (0.48) | MEN1KMT2AGAAGFERPTGER4 | |
| SCHEMBL11779282 | 0.80 | CA2 (0.38) | MEN1KMT2AGAAGFERMAPT | |
| SCHEMBL11779276 | 0.80 | CA2 (0.38) | MEN1KMT2AGAAGFERMAPT | |
| SCHEMBL11783471 | 0.79 | MEN1 (0.53) | MEN1KMT2AGAAGFERPTGER4 | |
| SCHEMBL11780536 | 0.78 | BDKRB1 (0.41) | MEN1KMT2AGAAGFERLMNA | |
| SCHEMBL11777642 | 0.75 | CA1 (0.48) | MEN1KMT2AGAAGFERMAPT | |
| SCHEMBL11802068 | 0.74 | CA2 (0.56) | MEN1KMT2AKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |