Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | YWHAG | P61981 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937244 | 0.83 | NPC1 (0.33) | NPC1HSD17B10 | |
| SCHEMBL5309405 | 0.71 | — | — | |
| SCHEMBL5813243 | 0.71 | — | — | |
| SCHEMBL31014270 | 0.69 | MEN1 (0.32) | HSD17B10L3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL5640982 | 0.63 | — | — | |
| SCHEMBL3785748 | 0.60 | — | — | |
| SCHEMBL5130701 | 0.60 | USP2 (0.32) | HPGDMAPK1 | |
| SCHEMBL6196492 | 0.57 | L3MBTL1 (0.34) | NPC1HSD17B10PARP1L3MBTL1HTT | |
| SCHEMBL7215990 | 0.57 | APAF1 (0.32) | — | |
| SCHEMBL1405516 | 0.57 | ACHE (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3993762-A | NON-NARCOTIC ANALGESICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-23 | — | — | US | disclosed |
| US-3933832-A | NON-NARCOTIC ANALGESICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-01-20 | — | — | US | disclosed |