Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611825 | 0.81 | CASR (0.39) | CASRMEN1KMT2ACNR1GAA | |
| SCHEMBL11983306 | 0.69 | TDP1 (0.39) | CASRTDP1GAACYP1A2CYP2D6 | |
| SCHEMBL11665566 | 0.68 | NFE2L2 (0.34) | CASRMEN1KMT2ACNR1TDP1 | |
| SCHEMBL10738990 | 0.66 | L3MBTL1 (0.41) | MEN1KMT2ATDP1GAACYP1A2 | |
| SCHEMBL11616522 | 0.66 | TRPA1 (0.40) | CASRHPGDNPC1 | |
| SCHEMBL11660365 | 0.66 | GAA (0.34) | CASRCNR1GAAPPARGPPARD | |
| SCHEMBL27571634 | 0.66 | GAA (0.44) | MEN1KMT2AGAACYP1A2CYP2D6 | |
| SCHEMBL22967388 | 0.65 | NPC1 (0.41) | TDP1GAACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11612984 | 0.65 | TSHR (0.50) | CASRMEN1KMT2ALMNATSHR | |
| SCHEMBL11023506 | 0.65 | TSHR (0.50) | CASRMEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |