Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774656 | 0.60 | PIM1 (0.39) | LMNAKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL6663539 | 0.59 | — | — | |
| SCHEMBL10498542 | 0.59 | LMNA (0.70) | LMNAKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL20138339 | 0.58 | KDM4E (0.52) | LMNAKDM4EALDH1A1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL27991536 | 0.58 | APOBEC3A (0.33) | — | |
| Hydrochloric Acid SCHEMBL1228298 | 0.57 | — | — | |
| SCHEMBL599355 | 0.56 | — | — | |
| SCHEMBL255331 | 0.56 | MAPT (0.57) | LMNAKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL18228600 | 0.56 | KDM4E (0.60) | LMNAKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL3339822 | 0.56 | KDM4E (0.60) | LMNAKDM4EALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |