Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989960 | 0.81 | KDM4E (0.39) | PIM1SCN9AALDH1A1SCN10AGRM5 | |
| SCHEMBL12427186 | 0.77 | CRBN (0.53) | PIM1SCN9AALDH1A1GRM5KDM4E | |
| SCHEMBL5613004 | 0.73 | LPO (0.35) | PIM1SCN9AALDH1A1SCN10AKDM4E | |
| SCHEMBL19402116 | 0.72 | IDH1 (0.47) | PIM1 | |
| SCHEMBL11659873 | 0.72 | DRD2 (0.54) | PIM1SCN9AALDH1A1NPC1RAB9A | |
| SCHEMBL4781538 | 0.72 | KDM4C (0.43) | SCN9AALDH1A1KDM4ENPC1RAB9A | |
| Benzene SCHEMBL28151588 | 0.71 | KMT2A (0.40) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2234870 | 0.71 | MEN1 (0.72) | NPC1RAB9ADRD2HTR2AMEN1 | |
| SCHEMBL27774657 | 0.71 | DRD2 (0.58) | PIM1SCN9AALDH1A1NPC1RAB9A | |
| SCHEMBL23126554 | 0.71 | HTR3E (0.51) | SCN9AALDH1A1SCN10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679291-A | Imidazolidine carboxamide derivatives as P2X7 modulators | GLAXO GROUP LTD | 2010-03-24 | — | — | CN | disclosed |