Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752750 | 0.79 | GPR3 (0.54) | DRD2CYP3A4HIF1AHSD17B10 | |
| SCHEMBL14004148 | 0.75 | CA1 (0.44) | CYP3A4CYP2D6NFKB1HIF1AHSD17B10 | |
| SCHEMBL11678333 | 0.75 | KCNH2 (0.50) | KCNH2THRATHRBBCHEDRD2 | |
| SCHEMBL2930647 | 0.72 | SLC6A2 (0.44) | DRD2CYP3A4HIF1AHSD17B10 | |
| SCHEMBL11780246 | 0.71 | HRH3 (0.47) | THRB | |
| SCHEMBL8752769 | 0.71 | SLC6A2 (0.53) | DRD2CYP3A4HIF1AHSD17B10 | |
| SCHEMBL1796223 | 0.70 | KDM4E (0.44) | BCHE | |
| SCHEMBL7557667 | 0.69 | SLC6A2 (0.45) | DRD2CYP3A4HIF1AHSD17B10 | |
| SCHEMBL5175599 | 0.67 | ADRA2A (0.66) | KCNH2THRATHRBBCHEDRD2 | |
| SCHEMBL8569852 | 0.67 | KCNH2 (0.80) | KCNH2DRD2DRD3OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3983124-A | ANTIVIRAL AGENTS | RICHARDSON-MERRELL INC. (US) | 1976-09-28 | — | — | US | disclosed |