SCHEMBL11780348

SCHEMBL11780348

CCOc1cccc(NC(=O)c2ccccc2C)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.67
RAB9A P51151 3/20 0.67
PKM P14618 1/20 0.67
KMT2A Q03164 6/20 0.64
KCNK3 O14649 5/20 0.64
KCNK9 Q9NPC2 5/20 0.64
F2R P25116 2/20 0.62
ALDH1A1 P00352 4/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
HPGD P15428 1/20 0.59
MEN1 O00255 3/20 0.59
NR1H4 Q96RI1 1/20 0.57
NPC1 O15118 2/20 0.56
GAA P10253 1/20 0.56
CASP3 P42574 1/20 0.56
SENP8 Q96LD8 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
LMNA P02545 2/20 0.56
FADS1 O60427 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11784409 0.90 LMNA (0.70) POLBRAB9APKMKMT2AKCNK3
SCHEMBL11779049 0.88 THRB (0.69) POLBRAB9APKMKMT2AKCNK3
SCHEMBL11783193 0.87 THRB (0.64) POLBRAB9APKMKMT2AKCNK3
SCHEMBL11786205 0.86 THRB (0.62) POLBRAB9APKMKMT2AKCNK3
SCHEMBL11780845 0.86 THRB (0.62) POLBRAB9APKMKMT2AKCNK3
SCHEMBL11779160 0.86 KMT2A (0.63) POLBRAB9AKMT2AKCNK3KCNK9
SCHEMBL11782583 0.85 GAA (0.75) POLBRAB9APKMKMT2AKCNK3
SCHEMBL11783890 0.85 GMPS (0.58) POLBRAB9APKMKMT2AKCNK3
SCHEMBL11332358 0.85 KCNK3 (0.58) POLBRAB9APKMKMT2AKCNK3
SCHEMBL4436642 0.85 KCNK3 (0.77) POLBRAB9AKMT2AKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3985804-A Agricultural substituted 2-methylbenzanilide germicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-10-12 US claimed
US-3985804-A Agricultural substituted 2-methylbenzanilide germicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-10-12 US disclosed
US-3937840-A COMPOSITIONS AND METHODS OF COMBATTING BACTERIA AND FUNGI USING 2-METHYLBENZANILIDE DERIVATIVES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-02-10 US disclosed