SCHEMBL11786205

SCHEMBL11786205

CCCCCCCCOc1cccc(NC(=O)c2ccccc2C)c1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.62
NR1H4 Q96RI1 6/20 0.61
LMNA P02545 1/20 0.60
F2R P25116 1/20 0.59
POLB P06746 2/20 0.57
KCNK3 O14649 2/20 0.57
KCNK9 Q9NPC2 2/20 0.57
KMT2A Q03164 2/20 0.57
PKM P14618 1/20 0.57
RAB9A P51151 1/20 0.57
ALDH1A1 P00352 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SMPD1 P17405 3/20 0.54
RXFP1 Q9HBX9 1/20 0.53
MEN1 O00255 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11780845 1.00 THRB (0.62) THRBNR1H4LMNAF2RPOLB
SCHEMBL11783193 0.99 THRB (0.64) THRBNR1H4LMNAF2RPOLB
SCHEMBL11779049 0.95 THRB (0.69) THRBNR1H4LMNAF2RPOLB
SCHEMBL11784409 0.91 LMNA (0.70) THRBNR1H4LMNAF2RPOLB
SCHEMBL11589558 0.87 THRB (0.61) THRBNR1H4LMNAKMT2AALDH1A1
SCHEMBL11332358 0.87 KCNK3 (0.58) THRBLMNAF2RPOLBKCNK3
SCHEMBL11780348 0.86 POLB (0.67) NR1H4LMNAF2RPOLBKCNK3
SCHEMBL11588440 0.86 THRB (0.62) THRBNR1H4LMNAKMT2AALDH1A1
SCHEMBL13719460 0.82 NPC1 (0.68) LMNAKMT2ARAB9AALDH1A1SMN1; SMN2
SCHEMBL9858310 0.82 NR1H4 (0.68) THRBNR1H4LMNASMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3985804-A Agricultural substituted 2-methylbenzanilide germicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-10-12 US disclosed
US-3937840-A COMPOSITIONS AND METHODS OF COMBATTING BACTERIA AND FUNGI USING 2-METHYLBENZANILIDE DERIVATIVES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-02-10 US disclosed