Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | PPIA | P62937 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770587 | 0.87 | RAB9A (0.48) | RAB9ANPC1PPIACTSLMEN1 | |
| SCHEMBL10490780 | 0.81 | KMT2A (0.59) | RAB9ANPC1PPIAMEN1KMT2A | |
| SCHEMBL87044 | 0.81 | POLB (0.61) | RAB9ANPC1PPIAMEN1KMT2A | |
| SCHEMBL6097282 | 0.80 | CYP19A1 (0.51) | NPC1L3MBTL1CYP19A1MEN1KMT2A | |
| SCHEMBL6672269 | 0.78 | RAB9A (0.61) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL9524996 | 0.78 | CXCR1 (0.60) | RAB9ANPC1CYP19A1CTSLMEN1 | |
| SCHEMBL6966891 | 0.77 | PLAU (0.59) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9524409 | 0.77 | NPC1 (0.64) | RAB9ANPC1L3MBTL1CYP19A1MEN1 | |
| SCHEMBL15516309 | 0.76 | NPC1 (0.66) | RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9588889 | 0.76 | NPC1 (0.70) | RAB9ANPC1L3MBTL1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052387-A | METHOD OF PREPARATION OF 3-METHYLENECEPHAMS | ELI LILLY AND COMPANY (US) | 1977-10-04 | — | — | US | disclosed |