Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CCR6 | P51684 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524996 | 0.86 | CXCR1 (0.60) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9524084 | 0.86 | LMNA (0.71) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2070549 | 0.84 | MAPT (0.70) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL5224480 | 0.83 | ALDH1A1 (0.65) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2070523 | 0.81 | CYP19A1 (0.76) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL2070181 | 0.81 | ALDH1A1 (0.65) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL31261387 | 0.81 | MAPT (0.59) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL1554137 | 0.80 | NPC1 (0.70) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9523344 | 0.80 | NPC1 (0.70) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14648942 | 0.80 | NPC1 (0.70) | NPC1RAB9AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285000-B1 | CHROMOGENE COMPOUNDS, THEIR MANUFACTURE AND USE AS ENZYME SUBSTRATES | Roche Diagnostics GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-5190862-A | Peptide modified compound | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5108890-A | Diagnostic agents for determining peptide bond-cleaving enzymes; measuring light absorbed by liberated colored materials | BOEHRINGER MANNHEIM GMBH (DE) | 1992-04-28 | — | — | US | disclosed |