Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522410 | 0.82 | L3MBTL1 (0.71) | HTTL3MBTL1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9167530 | 0.81 | L3MBTL1 (0.56) | KMT2AHTTL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL6096285 | 0.81 | L3MBTL1 (0.56) | KMT2AHTTL3MBTL1MEN1POLB | |
| SCHEMBL28055704 | 0.81 | PTPRF (0.56) | CYP19A1KMT2AHTTL3MBTL1MEN1 | |
| SCHEMBL11780366 | 0.80 | RAB9A (0.55) | CYP19A1KMT2AL3MBTL1MEN1SMN1; SMN2 | |
| SCHEMBL6097904 | 0.80 | L3MBTL1 (0.55) | HTTL3MBTL1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL13240460 | 0.78 | KMT2A (0.49) | KMT2AHTTMEN1POLBMAPT | |
| SCHEMBL28220176 | 0.77 | ALDH1A1 (0.58) | KMT2AHTTL3MBTL1MEN1POLB | |
| SCHEMBL8813875 | 0.77 | MAPT (0.55) | CYP19A1RORCKMT2AMEN1POLB | |
| SCHEMBL7484877 | 0.77 | TSHR (0.58) | KMT2AL3MBTL1MEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115745-B2 | Benzyl urea and thiourea derivatives | WARNER LAMBERT COMPANY LLC (US) | 2006-10-03 | — | — | US | disclosed |
| US-20050107427-A1 | Benzyl urea and thiourea derivatives | DU DANIEL Y (US) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107427-A1 | Benzyl urea and thiourea derivatives | BRDT, TAS2R8, FSHR | CYP19A1 31/4885RORC 398/4885KMT2A 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.