Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785302 | 0.81 | ALDH1A1 (0.34) | LMNAALPLALPIALDH1A1KDM5B | |
| SCHEMBL11785306 | 0.81 | ALDH1A1 (0.34) | LMNAALPLALPIALDH1A1KDM5B | |
| SCHEMBL25153650 | 0.80 | ALDH1A1 (0.40) | LMNAALPLALPIALDH1A1KDM5B | |
| SCHEMBL11784400 | 0.75 | ALDH1A1 (0.39) | LMNAADORA2BALPLALPIALDH1A1 | |
| SCHEMBL2608960 | 0.74 | POLB (0.41) | ALDH1A1KDM5BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27372069 | 0.74 | ADORA2B (0.39) | ADORA2BALDH1A1KDM5BNPSR1NPC1 | |
| SCHEMBL11783018 | 0.72 | ALDH1A1 (0.34) | LMNAALPLALPIALDH1A1KDM5B | |
| SCHEMBL11788419 | 0.72 | PKM (0.45) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL11785413 | 0.71 | SMN1; SMN2 (0.42) | LMNAALPLALPIALDH1A1ADORA2A | |
| SCHEMBL11782878 | 0.71 | SMN1; SMN2 (0.42) | LMNAALPLALPIALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981715-A | 2,3,5-Substituted-6-trifluoromethyl-1,3-diazin-4-ones herbicides | AMERICAN CYANAMID COMPANY (US) | 1976-09-21 | — | — | US | disclosed |