Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624410 | 0.81 | EEF2K (0.39) | EEF2KLMNACYP2D6CYP2C9TSHR | |
| SCHEMBL9814357 | 0.80 | KCNH2 (0.41) | LMNACYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL9814361 | 0.80 | KCNH2 (0.41) | LMNACYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL4626358 | 0.80 | LMNA (0.41) | LMNACYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL11780449 | 0.78 | EEF2K (0.44) | EEF2KLMNACYP2D6CYP2C9TSHR | |
| SCHEMBL7776941 | 0.74 | EEF2K (0.61) | EEF2KLMNAHTT | |
| SCHEMBL11785048 | 0.73 | CA1 (0.69) | EEF2KLMNACYP2D6CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL7775450 | 0.73 | EEF2K (0.59) | EEF2KLMNAHTT | |
| Hydrochloric Acid SCHEMBL11786436 | 0.73 | EEF2K (0.59) | EEF2KLMNAHTT | |
| SCHEMBL28452168 | 0.70 | HTT (0.69) | LMNACYP2D6CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931129-A | FLUOROELASTOMER COMPOSITION | DAIKIN KOGYO CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |