SCHEMBL11780922

SCHEMBL11780922

COP(=O)(CO)Cc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.57
POLB P06746 2/20 0.49
LMNA P02545 1/20 0.49
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
LAP3 P28838 1/20 0.45
TSHR P16473 4/20 0.41
ACP3 P15309 2/20 0.39
HTT P42858 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GAA P10253 1/20 0.38
ALDH1A1 P00352 1/20 0.38
BTN3A1 O00481 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL563403 0.88 MEN1 (0.51) HPGDPOLBLMNAMEN1KMT2A
SCHEMBL3367720 0.79 TSHR (0.58) HPGDPOLBLMNATSHRALDH1A1
SCHEMBL232550 0.76 LAP3 (0.51) HPGDPOLBLMNAMEN1KMT2A
SCHEMBL28883513 0.75 HPGD (0.54) HPGDMEN1KMT2ALAP3TSHR
SCHEMBL563700 0.75 HPGD (0.48) HPGDPOLBLMNAMEN1KMT2A
SCHEMBL20826937 0.74 HPGD (0.52) HPGDLMNAMEN1KMT2ATSHR
SCHEMBL9761734 0.74 MEN1 (0.51) HPGDPOLBMEN1KMT2ALAP3
SCHEMBL11605919 0.74 HPGD (0.47) HPGDPOLBLMNAMEN1KMT2A
SCHEMBL563856 0.72 NPSR1 (0.50) HPGDPOLBMEN1KMT2ATSHR
SCHEMBL3367144 0.72 TSHR (0.64) HPGDPOLBLMNATSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3943170-A Process for the preparation of halo-methylphosphinic acid halides HOECHST AKTIENGESELLSCHAFT (DT) 1976-03-09 US disclosed