Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367144 | 0.90 | TSHR (0.64) | TSHRHPGDSRCCETPPDPK1 | |
| SCHEMBL11511859 | 0.82 | TSHR (0.55) | TSHRHPGDSRCCETPALDH1A1 | |
| SCHEMBL11780922 | 0.79 | HPGD (0.57) | TSHRHPGDALDH1A1LMNAPOLB | |
| SCHEMBL4641409 | 0.79 | TSHR (0.64) | TSHRHPGDSRCCETPPDPK1 | |
| SCHEMBL7631529 | 0.77 | TSHR (0.68) | TSHRHPGDSRCCETPPDPK1 | |
| SCHEMBL4154492 | 0.76 | TSHR (0.56) | TSHRHPGDSRCCETPPDPK1 | |
| SCHEMBL5850148 | 0.76 | TSHR (0.61) | TSHRHPGDSRCCETPPDPK1 | |
| SCHEMBL7520596 | 0.76 | TSHR (0.67) | TSHRHPGDSRCCETPPDPK1 | |
| Hydrochloric Acid SCHEMBL7372995 | 0.76 | TSHR (0.66) | TSHRHPGDSRCCETPPDPK1 | |
| SCHEMBL4247405 | 0.76 | TSHR (0.55) | TSHRHPGDSRCCETPPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056795-A1 | NOVEL SYNTHETIC DINUCLEOSIDE POLYPHOSPHATE ANALOGS AND THEIR USE AS NEW THERAPEUTIC AND/OR DIAGNOSTIC MODALITIES | ZATA PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |