Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KYNU | Q16719 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483591 | 0.88 | MEN1 (0.42) | MEN1KMT2AHPGDKYNUL3MBTL1 | |
| SCHEMBL7916451 | 0.81 | AOX1 (0.58) | MEN1KMT2AHPGDL3MBTL1POLB | |
| SCHEMBL18486477 | 0.79 | L3MBTL1 (0.56) | MEN1KMT2AHPGDKYNUL3MBTL1 | |
| SCHEMBL777171 | 0.79 | AOX1 (0.47) | MEN1KMT2AHPGDKYNUL3MBTL1 | |
| SCHEMBL4247405 | 0.78 | TSHR (0.55) | MEN1KMT2AHPGDKYNUAOX1 | |
| SCHEMBL1967085 | 0.78 | L3MBTL1 (0.53) | MEN1KMT2AHPGDL3MBTL1HTT | |
| SCHEMBL563403 | 0.77 | MEN1 (0.51) | MEN1KMT2AHPGDL3MBTL1HTT | |
| SCHEMBL563700 | 0.77 | HPGD (0.48) | MEN1KMT2AHPGDL3MBTL1HTT | |
| SCHEMBL100465 | 0.77 | GAA (0.70) | MEN1KMT2AHPGDHTTHDAC1 | |
| SCHEMBL5485179 | 0.76 | L3MBTL1 (0.52) | MEN1KMT2AKYNUL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082057-B1 | PROCESS FOR PREPARING PHOSPHINAMIDES, APPLICATIONS AND PRODUCTS | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1986-04-30 | — | — | EP | claimed |
| WO-2013040790-A1 | SUBSTITUTED PYRIMIDINES | MERCK SHARP & DOHME CORP. (US) | 2013-03-28 | — | — | WO | disclosed |
| US-5068425-A | Nervous system disorders, intermediates for drugs and as enantiomorphs | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-11-26 | — | — | US | disclosed |
| US-4983768-A | Reacting an organic halide and an oxazaphospholidine in the absence of air, humidity and light | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1991-01-08 | — | — | US | disclosed |