Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830681 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL27712566 | 0.79 | MAPT (0.58) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL6017146 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL27683334 | 0.77 | KDM4E (0.55) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL13963798 | 0.75 | MAPT (0.55) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL3017219 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9390432 | 0.74 | ALOX5 (0.54) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27538582 | 0.74 | SREBF2 (0.44) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL1821255 | 0.74 | KDM4E (0.72) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL27541634 | 0.74 | NPC1 (0.52) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033977-A | ANTIINFLAMMATORY, ANTIDEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |