SCHEMBL117832

SCHEMBL117832

COC(=O)C(C)(C)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphonic Acid SCHEMBL17183012 0.89 DGAT1 (0.39)
Adamantane SCHEMBL28643307 0.85 EPHX2 (0.37)
SCHEMBL27622606 0.81
SCHEMBL4300520 0.81 DGAT1 (0.46)
SCHEMBL30688676 0.80 KCNN4 (0.34)
SCHEMBL5159118 0.78 PRSS1 (0.32)
SCHEMBL10954143 0.78 KCNN4 (0.42)
SCHEMBL5613155 0.78
SCHEMBL13083667 0.77 DGAT1 (0.42)
SCHEMBL98576 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2005 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037095-A PVP-b-PMMA block polymer, preparation method thereof and ultrafiltration membrane 上海宇昂水性新材料科技股份有限公司 2026-05-15 CN claimed
CN-122037073-A Hyperbranched structure grafting-based shrinkage reducing agent for UHPC and preparation method thereof 福建农林大学 2026-05-15 CN claimed
CN-120058267-A Efficient concrete water reducer and preparation method thereof 中建(广州)工程检测有限公司 2025-05-30 CN claimed
CN-120058374-A Ceramic matrix composite material taking modified silicon carbide as precursor and preparation method thereof 福建立亚化学有限公司 2025-05-30 CN claimed
CN-119859208-A Binary free radical polymerization method 上海交通大学 2025-04-22 CN claimed
CN-118878521-B Preparation method of LRRK2 inhibitor 苏州美诺医药科技有限公司 2025-02-14 CN claimed
CN-115959993-B Synthesis method of 2-aryl propionic acid compound 山东中医药大学 2025-01-07 CN claimed
EP-3692081-B1 NOVEL GRAFT POLYMERS, METHODS FOR PREPARING SAME, AND USES THEREOF PARTICULARLY FOR METAL CAPTURE UNIV PARIS SACLAY (FR) 2024-12-04 EP claimed
CN-118878521-A Preparation method of LRRK2 inhibitor 苏州美诺医药科技有限公司 2024-11-01 CN claimed
EP-4442318-A2 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC (US) 2024-10-09 EP claimed
EP-3042645-A1 Dental composites with improved storage stability Ivoclar Vivadent AG (LI) 2016-07-13 EP claimed
US-20160102163-A1 FLAME RETARDANT ACRYLIC/PLA COPOLYMER INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-04-14 US claimed
CN-102358748-B Star chain transferring agent using cyclotriphosphazene as nucleus, and preparation method and application thereof UNIV YUNNAN NORMAL 2013-10-16 CN claimed
EP-1387822-B1 2-[4-(2,2,-DIHALOCYCLOPROPYL)PHENOXY]-ALKANOIC ACIDS AND ESTERS THEREOF PRODUCTION PROCESS LABORATORIO CHIMICO INT SPA (IT) 2005-06-15 EP claimed
EP-1387822-A1 2-[4-(2,2,-DIHALOCYCLOPROPYL)PHENOXY]-ALKANOIC ACIDS AND ESTERS THEREOF PRODUCTION PROCESS LABORATORIO CHIMICO INTERNAZIONALE S.p.A. (IT) 2004-02-11 EP claimed
US-20030144441-A1 Controlled copolymerization of methyl acrylate with olefins under mild conditions PENN STATE RESEARCH FOUNDATION, THE 2003-07-31 US claimed
WO-2003042254-A1 CONTROLLED COPOLYMERIZATION OF METHYL ACRYLATE WITH OLEFINS UNDER MILD CONDITIONS THE PENN STATE RESEARCH FOUNDATION (US) 2003-05-22 WO claimed
WO-2002090307-A1 2-[4-(2, 2-DIHALOCYCLOPROPYL)PHENOXY]-ALKANOIC ACIDS AND ESTERS THEREOF PRODUCTION PROCESS LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) 2002-11-14 WO claimed
US-5071991-A METHOD OF PREPARING CHROMAN DERIVATIVES, AND SYNTHESIS INTERMEDIATES SANOFI (FR) 1991-12-10 US claimed
US-4783543-A REACTING CARBOXYLIC ESTER WITH ALKALI METAL IN PRESENCE OF EXCESS ORGANOHALOSILANE DOW CORNING CORPORATION (US) 1988-11-08 US claimed