SCHEMBL98576

SCHEMBL98576

COC(=O)C(C)(F)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL543581 0.80
SCHEMBL226311 0.77
SCHEMBL117832 0.77
SCHEMBL4300520 0.77 DGAT1 (0.46)
SCHEMBL135961 0.77
SCHEMBL27622606 0.77
SCHEMBL9345959 0.77 DGAT1 (0.46)
SCHEMBL3205620 0.76 ALDH1A1 (0.39)
SCHEMBL28035795 0.74
SCHEMBL31058002 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591223-B Beta-lactamase inhibitor compounds 恩塔西斯治疗有限公司 2025-01-24 CN disclosed
US-20240425505-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2024-12-26 US disclosed
US-12110290-B2 Triazolopyridinyl compounds as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2024-10-08 US disclosed
EP-4364737-A2 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS Bristol-Myers Squibb Company (US) 2024-05-08 EP disclosed
EP-4229056-B1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2024-04-10 EP disclosed
US-20240109888-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2024-04-04 US disclosed
US-11767322-B2 Triazolopyridinyl compounds as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2023-09-26 US disclosed
CN-116802181-A Triazolopyridine compounds as kinase inhibitors 百时美施贵宝公司 2023-09-22 CN disclosed
EP-4229056-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS Bristol-Myers Squibb Company (US) 2023-08-23 EP disclosed
EP-3512851-B1 BETA-LACTAMASE INHIBITOR COMPOUNDS ENTASIS THERAPEUTICS LTD (GB) 2022-07-06 EP disclosed
EP-3512851-A1 BETA-LACTAMASE INHIBITOR COMPOUNDS Entasis Therapeutics Limited (GB) 2019-07-24 EP disclosed
US-20190202832-A1 BETA-LACTAMASE INHIBITOR COMPOUNDS ENTASIS THERAPEUTICS LIMITED (GB) 2019-07-04 US disclosed
WO-2018053215-A1 BETA-LACTAMASE INHIBITOR COMPOUNDS ENTASIS THERAPEUTICS LIMITED (GB) 2018-03-22 WO disclosed
US-8450520-B2 Process for preparation of 2-fluoroacrylic esters CENTRAL GLASS COMPANY, LIMITED (JP) 2013-05-28 US disclosed
US-8450520-B2 Process for preparation of 2-fluoroacrylic esters CENTRAL GLASS COMPANY, LIMITED (JP) 2013-05-28 US disclosed
US-8450520-B2 Process for preparation of 2-fluoroacrylic esters CENTRAL GLASS COMPANY, LIMITED (JP) 2013-05-28 US disclosed
EP-2444389-A1 PROCESS FOR PREPARATION OF 2-FLUOROACRYLIC ESTERS Central Glass Company, Limited (JP) 2012-04-25 EP disclosed
US-20120059187-A1 Process for Preparation of 2-Fluoroacrylic Esters CENTRAL GLASS COMPANY, LIMITED (JP) 2012-03-08 US disclosed
US-20120059187-A1 Process for Preparation of 2-Fluoroacrylic Esters CENTRAL GLASS COMPANY, LIMITED (JP) 2012-03-08 US disclosed
US-20120059187-A1 Process for Preparation of 2-Fluoroacrylic Esters CENTRAL GLASS COMPANY, LIMITED (JP) 2012-03-08 US disclosed