Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11784883 | 0.98 | FAAH (0.52) | FAAHCYP1A2CYP3A4HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11782659 | 0.84 | FAAH (0.53) | FAAHCLK4 | |
| SCHEMBL11786092 | 0.79 | CYP1A2 (0.56) | FAAHCYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL18902711 | 0.76 | CYP1A2 (0.53) | FAAHCYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL14133140 | 0.75 | CYP1A2 (0.54) | FAAHCYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL20816281 | 0.73 | CYP1A2 (0.62) | FAAHCYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL15473076 | 0.73 | FLT3 (0.36) | FAAHCYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL14132888 | 0.73 | FAAH (0.48) | FAAHCYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL3431292 | 0.72 | FAAH (0.83) | FAAH | |
| SCHEMBL17700215 | 0.71 | THRB (0.45) | CYP1A2CYP3A4HSD17B10CYP2D6CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950525-A | BRONCHODILATION, 4-HYDROXY-6-ARYL PYRIMIDINES | PFIZER INC. (US) | 1976-04-13 | — | — | US | disclosed |