Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786450 | 0.80 | MAP2K7 (0.35) | TSHRALOX15CYP1A2ALDH1A1GAA | |
| SCHEMBL1535710 | 0.78 | BCHE (0.54) | TSHRALOX15CYP1A2BCHEACHE | |
| SCHEMBL1495342 | 0.76 | BCHE (0.57) | TSHRALOX15CYP1A2BCHEACHE | |
| SCHEMBL6583705 | 0.73 | POLB (0.37) | CYP1A2SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL8952775 | 0.72 | BCHE (0.55) | BCHEACHESMN1; SMN2RAB9ATP53 | |
| SCHEMBL28050241 | 0.70 | RAB9A (0.68) | ALOX15CYP1A2BCHESMN1; SMN2RAB9A | |
| SCHEMBL1036360 | 0.70 | LMNA (0.34) | CYP1A2CYP3A4LMNAALDH1A1MAPT | |
| SCHEMBL28728369 | 0.69 | RAB9A (0.66) | ALOX15CYP1A2BCHESMN1; SMN2RAB9A | |
| SCHEMBL861074 | 0.69 | RAB9A (0.49) | ALOX15BCHESMN1; SMN2RAB9ATP53 | |
| SCHEMBL8214299 | 0.69 | RAB9A (0.46) | ALOX15SMN1; SMN2RAB9ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1256691-A | 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists | PROCTER & GAMBLE (US) | 2000-06-14 | — | — | CN | disclosed |
| US-3935314-A | Anti-hypertensive compositions of benzimidazole derivatives | BEECHAM GROUP LIMITED (EN) | 1976-01-27 | — | — | US | disclosed |