Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535710 | 0.98 | BCHE (0.54) | BCHEACHERAB9ASMN1; SMN2GAA | |
| SCHEMBL11784173 | 0.76 | TSHR (0.48) | BCHEACHERAB9ASMN1; SMN2GAA | |
| SCHEMBL29647608 | 0.74 | CYP3A4 (0.61) | BCHERAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL1800355 | 0.74 | CYP3A4 (0.61) | BCHERAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL8567589 | 0.74 | TSHR (0.78) | BCHEACHERAB9ASMN1; SMN2GAA | |
| SCHEMBL28050241 | 0.74 | RAB9A (0.68) | BCHERAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL1535706 | 0.73 | LMNA (0.63) | RAB9ASMN1; SMN2GAATDP1ALDH1A1 | |
| SCHEMBL717865 | 0.72 | BCHE (1.00) | BCHEACHERAB9ASMN1; SMN2MAPT | |
| SCHEMBL2241920 | 0.72 | BCHE (1.00) | BCHEACHERAB9ASMN1; SMN2MAPT | |
| SCHEMBL28728369 | 0.72 | RAB9A (0.66) | BCHERAB9ASMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505543-A1 | NOVEL p-SUBSTITUTED PHENYL 4-OXYBUTANE AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRE THERAMEX (MC) | 1992-09-30 | — | — | EP | claimed |
| WO-1992006977-A1 | NOVEL p-SUBSTITUTED PHENYL 4-OXYBUTANE AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRE THERAMEX S.A. (MC) | 1992-04-30 | — | — | WO | claimed |
| CN-106663544-B | Photo-electric conversion element, dye-sensitized solar cells, metal complex dye, pigment solution and terpyridyl or its carboxylate | 富士胶片株式会社 | 2018-06-29 | — | — | CN | disclosed |
| CN-106663544-A | Photoelectric conversion element, dye-sensitized solar cell, metal-complex pigment, pigment solution, and terpyridine compound or esterified terpyridine compound | 富士胶片株式会社 | 2017-05-10 | — | — | CN | disclosed |
| CN-103450159-A | Piperidine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARM LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-103450159-A | Piperidine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARM LTD | 2013-12-18 | — | — | CN | disclosed |
| EP-1723136-B1 | PIPERIDINE-AMINO-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARM LTD (IE) | 2011-03-09 | — | — | EP | disclosed |
| EP-1723136-B1 | PIPERIDINE-AMINO-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARM LTD (IE) | 2011-03-09 | — | — | EP | disclosed |
| US-20080146613-A1 | PIPERIDINE-AMINO-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-06-19 | — | — | US | disclosed |
| US-20080146613-A1 | PIPERIDINE-AMINO-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-06-19 | — | — | US | disclosed |
| US-7355051-B2 | Piperdine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARMACEUTICALS (IE) | 2008-04-08 | — | — | US | disclosed |
| US-20070093659-A1 | Piperdine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication | JANSSEN SCIENCES IRELAND UC (IE) | 2007-04-26 | — | — | US | disclosed |
| US-20070093659-A1 | Piperdine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication | JANSSEN SCIENCES IRELAND UC (IE) | 2007-04-26 | — | — | US | disclosed |
| CN-1894239-A | Piperidine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARM LTD (IE) | 2007-01-10 | — | — | CN | disclosed |
| CN-1894239-A | Piperidine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARM LTD (IE) | 2007-01-10 | — | — | CN | disclosed |
| EP-1723136-A1 | PIPERIDINE-AMINO-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Tibotec Pharmaceuticals Ltd. (IE) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005058873-A1 | PIPERIDINE-AMINO-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |
| US-5461059-A | Antihistamine; treats allergies and asthma | LABORATOIRE THERAMEX S.A. (FR) | 1995-10-24 | — | — | US | disclosed |
| EP-0505543-A1 | NOVEL p-SUBSTITUTED PHENYL 4-OXYBUTANE AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRE THERAMEX (MC) | 1992-09-30 | — | — | EP | disclosed |
| WO-1992006977-A1 | NOVEL p-SUBSTITUTED PHENYL 4-OXYBUTANE AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRE THERAMEX S.A. (MC) | 1992-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093659-A1 | Piperdine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication | NQO2, NOX1, NOX3 | BCHE 4457/4885ACHE 4724/4885RAB9A 223/4885 |
| US-20080146613-A1 | PIPERIDINE-AMINO-BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | NQO2, NOX3, NOX1 | BCHE 4621/4885ACHE 4744/4885RAB9A 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.