Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GPX4 | P36969 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787165 | 0.99 | NPC1 (0.62) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL11785174 | 0.90 | TP53 (0.49) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL11489788 | 0.85 | NPC1 (0.62) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL11786185 | 0.83 | ALDH1A1 (0.58) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL11793748 | 0.83 | NPC1 (0.56) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL11785977 | 0.82 | NPC1 (0.58) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL607964 | 0.80 | NPC1 (0.67) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL28391957 | 0.79 | NPC1 (0.62) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL7388943 | 0.79 | NPC1 (0.69) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL9809230 | 0.79 | NPC1 (0.69) | NPC1RAB9APAX8JAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969406-A | Process for the production of carnitine | LONZA LTD. (CH) | 1976-07-13 | — | — | US | disclosed |