Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785174 | 0.87 | TP53 (0.49) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11897377 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11788895 | 0.84 | GPR88 (0.42) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11786157 | 0.83 | NPC1 (0.59) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11618038 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11787165 | 0.82 | NPC1 (0.62) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11787275 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL4055696 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL18765958 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11211970 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRGLATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969406-A | Process for the production of carnitine | LONZA LTD. (CH) | 1976-07-13 | — | — | US | disclosed |