Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383830 | 0.90 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL11382132 | 0.88 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL11379351 | 0.87 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL11379786 | 0.83 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL11743164 | 0.79 | — | — | |
| SCHEMBL11387518 | 0.78 | RAB9A (0.49) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL11738579 | 0.78 | — | — | |
| SCHEMBL31545877 | 0.78 | — | — | |
| SCHEMBL11376381 | 0.75 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL4506446 | 0.75 | ALDH1A1 (0.68) | ALDH1A1NPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947462-A | 2,4,7-substituted 5-hydroxy benzopyrans and esters | ABBOTT LABORATORIES (US) | 1976-03-30 | — | — | US | disclosed |