Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | DHPS | P49366 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487045 | 0.91 | LMNA (0.71) | RAB9ALMNANR1I3SMN1; SMN2KMT2A | |
| SCHEMBL3766697 | 0.85 | RAB9A (0.73) | RAB9ANR1I3SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL2798866 | 0.84 | RAB9A (0.61) | RAB9ALMNANR1I3SMN1; SMN2KMT2A | |
| SCHEMBL21207988 | 0.84 | RAB9A (0.61) | RAB9ALMNANR1I3SMN1; SMN2KMT2A | |
| SCHEMBL4546968 | 0.83 | RAB9A (0.70) | RAB9ANR1I3SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL29786739 | 0.82 | RAB9A (0.50) | RAB9ALMNASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL10595789 | 0.82 | RAB9A (0.50) | RAB9ALMNASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL22883197 | 0.81 | LMNA (0.58) | RAB9ALMNANR1I3SMN1; SMN2KMT2A | |
| SCHEMBL5483462 | 0.81 | LMNA (0.48) | RAB9ALMNASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4546940 | 0.81 | RAB9A (0.68) | RAB9ANR1I3SMN1; SMN2KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |