Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.58 |
| ▸ | CA1 | P00915 | 9/20 | 0.58 |
| ▸ | CA2 | P00918 | 9/20 | 0.58 |
| ▸ | CA3 | P07451 | 9/20 | 0.58 |
| ▸ | CA6 | P23280 | 9/20 | 0.58 |
| ▸ | CA5A | P35218 | 9/20 | 0.58 |
| ▸ | CA7 | P43166 | 9/20 | 0.58 |
| ▸ | CA13 | Q8N1Q1 | 9/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 9/20 | 0.58 |
| ▸ | CA4 | P22748 | 8/20 | 0.58 |
| ▸ | CA9 | Q16790 | 8/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.58 |
| ▸ | CISD1 | Q9NZ45 | 9/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788659 | 0.86 | CA12 (0.67) | CA12CA1CA2CA3CA6 | |
| SCHEMBL8575392 | 0.79 | CA12 (0.61) | CA12CA1CA2CA3CA6 | |
| SCHEMBL8576948 | 0.79 | GABRP (0.48) | CA12CA1CA2CA3CA6 | |
| SCHEMBL8572973 | 0.77 | CA12 (0.67) | CA12CA1CA2CA3CA6 | |
| SCHEMBL11804030 | 0.75 | CA12 (0.59) | CA12CA1CA2CA3CA6 | |
| SCHEMBL18424444 | 0.74 | CA12 (1.00) | CA12CA1CA2CA3CA6 | |
| Phthalic Acid SCHEMBL27323736 | 0.74 | CA9 (0.51) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL8585576 | 0.74 | CA2 (0.42) | CA12CA1CA2CA3CA6 | |
| SCHEMBL8583944 | 0.74 | SLC9A1 (0.51) | — | |
| SCHEMBL8582895 | 0.72 | CA2 (0.46) | CA12CA1CA2CA3CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991188-A | SALURETICS | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-11-09 | — | — | US | disclosed |