Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | BCR | P11274 | 2/20 | 0.49 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492830 | 0.92 | MAPT (0.73) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5250932 | 0.84 | MEN1 (0.80) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL11788000 | 0.84 | KMT2A (0.74) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5249571 | 0.83 | MAPT (1.00) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5250046 | 0.83 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL3604286 | 0.81 | KMT2A (0.74) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL22492842 | 0.81 | LMNA (0.69) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL22492802 | 0.81 | LMNA (0.54) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL11790155 | 0.78 | KMT2A (0.69) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL8691427 | 0.77 | ALDH1A1 (0.55) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188763-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | UNIV CALIFORNIA (US) | 2021-06-24 | — | — | US | disclosed |
| US-20210188763-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | UNIV CALIFORNIA (US) | 2021-06-24 | — | — | US | disclosed |
| EP-3717450-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | The Regents of the University of California (US) | 2020-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188763-A1 | COMPOUNDS AND METHODS FOR HEMATOPOIETIC REGENERATION | HGF, CXCL12, CCL11 | MEN1 4094/4885KMT2A 938/4885NPC1 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.