Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CRHBP | P24387 | 2/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163411 | 0.87 | SMN1; SMN2 (0.53) | ALDH1A1TDP1TSHRMAPTLMNA | |
| SCHEMBL5272077 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TDP1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6156984 | 0.84 | CRHBP (0.65) | ALDH1A1TDP1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5517557 | 0.84 | CXCR2 (0.50) | ALDH1A1TDP1TSHRMAPTLMNA | |
| SCHEMBL4467380 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRMAPTLMNA | |
| SCHEMBL27691846 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRMAPTLMNA | |
| SCHEMBL125017 | 0.83 | MAPT (0.55) | ALDH1A1TDP1TSHRMAPTLMNA | |
| SCHEMBL3862080 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRMAPTLMNA | |
| SCHEMBL11645653 | 0.81 | SMN1; SMN2 (0.56) | ALDH1A1TSHRMAPTLMNASMN1; SMN2 | |
| SCHEMBL124625 | 0.80 | HTT (0.63) | ALDH1A1MAPTLMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3970423-A | PHENYLENEDIAMINE DERIVATIVES | CLAIROL INCORPORATED (US) | 1976-07-20 | — | — | US | disclosed |