Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517557 | 0.87 | CXCR2 (0.50) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL6156984 | 0.87 | CRHBP (0.65) | SMN1; SMN2ALDH1A1MAPTHTTTDP1 | |
| SCHEMBL11788134 | 0.87 | ALDH1A1 (0.56) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL11645653 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL125017 | 0.85 | MAPT (0.55) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL124625 | 0.83 | HTT (0.63) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL124120 | 0.82 | CYP19A1 (0.54) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL9877920 | 0.81 | CYP19A1 (0.44) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL14940853 | 0.79 | CYP19A1 (0.50) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL28026309 | 0.77 | TSHR (0.67) | SMN1; SMN2LMNAALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2579841-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | L'Oréal (FR) | 2013-04-17 | — | — | EP | disclosed |
| WO-2011154458-A1 | COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS | L'OREAL (FR) | 2011-12-15 | — | — | WO | disclosed |
| EP-0531738-B2 | Two-pack type keratinous fiber treating composition | KAO CORP (JP) | 2005-02-16 | — | — | EP | disclosed |
| US-5750099-A | Two-pack type keratinous fiber treating composition | KAO CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0503507-B1 | Dye composition for keratinous fibers | KAO CORP (JP) | 1997-07-23 | — | — | EP | disclosed |
| EP-0531738-B1 | Two-pack type keratinous fiber treating composition | KAO CORP (JP) | 1996-11-13 | — | — | EP | disclosed |
| EP-0547790-B1 | Dye composition for Keratinous fibers | KAO CORP (JP) | 1995-08-23 | — | — | EP | disclosed |
| EP-0547790-A1 | Dye composition for Keratinous fibers | Kao Corporation (JP) | 1993-06-23 | — | — | EP | disclosed |
| EP-0531738-A2 | Two-pack type keratinous fiber treating composition | KAO CORPORATION (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0503507-A1 | Dye composition for keratinous fibers | Kao Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |