Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 6/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 4/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853419 | 0.83 | PARP1 (0.63) | PARP1PARP3PARP2 | |
| Hydrochloric Acid SCHEMBL854346 | 0.82 | PARP1 (0.62) | PARP1PARP3PARP2TP53MAPK1 | |
| SCHEMBL3555901 | 0.80 | HTR2A (0.58) | ALDH1A1ESR1ESR2HTR6HTR2A | |
| SCHEMBL12466150 | 0.80 | ESR1 (0.50) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL854643 | 0.77 | PARP1 (0.60) | PARP1PARP3PARP2 | |
| SCHEMBL854296 | 0.76 | PARP1 (0.56) | PARP1PARP3PARP2 | |
| SCHEMBL634936 | 0.76 | LTA4H (0.57) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL854243 | 0.75 | PARP1 (0.55) | PARP1PARP3PARP2 | |
| SCHEMBL854145 | 0.75 | PARP1 (0.55) | PARP1PARP3PARP2 | |
| SCHEMBL6826115 | 0.74 | TUBB4A (0.57) | KDM4EALDH1A1ESR1ESR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956267-A | Indole-containing disazo dyestuffs having a sulfatoalkyleneoxy-substituent | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |