Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | ATP4A | P20648 | 1/20 | 0.44 |
| ▸ | ATP4B | P51164 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264636 | 0.81 | CYP2D6 (0.56) | PTGS2LMNAMAPTADORA1MEN1 | |
| SCHEMBL10395225 | 0.80 | LMNA (0.56) | PTGS2LMNAMAPTADORA1ADORA3 | |
| SCHEMBL6176547 | 0.80 | PTGS2 (0.52) | PTGS2LMNAMAPTMEN1KMT2A | |
| SCHEMBL3162625 | 0.80 | ADORA2A (0.51) | PTGS2LMNAMAPTADORA1ADORA3 | |
| SCHEMBL27615750 | 0.80 | HRH4 (0.48) | PTGS2LMNAMAPTADORA1ADORA3 | |
| SCHEMBL12886474 | 0.79 | ADORA1 (0.45) | ADORA1ADORA3ADORA2AADORA2BCYP1A2 | |
| SCHEMBL11789945 | 0.78 | MAPT (0.50) | PTGS2LMNAMAPTADORA1ADORA3 | |
| SCHEMBL13920230 | 0.77 | ADORA3 (0.75) | MAPTADORA1ADORA3ADORA2AMEN1 | |
| SCHEMBL3163367 | 0.77 | ADORA1 (0.56) | PTGS2LMNAMAPTADORA1ADORA3 | |
| SCHEMBL11798033 | 0.77 | LMNA (0.47) | PTGS2LMNAMAPTADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |