Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | TRHR | P34981 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11585814 | 0.90 | ACE (0.49) | ACEDPP4DPP8RENPREP | |
| SCHEMBL7523931 | 0.89 | ACE (0.52) | ACEDPP4DPP8RENPREP | |
| SCHEMBL7271897 | 0.87 | ACE (0.53) | ACEDPP4DPP8RENACE2 | |
| SCHEMBL11332063 | 0.85 | ACE (0.45) | ACERENTRHR | |
| SCHEMBL11333608 | 0.85 | ACE (0.45) | ACERENTRHR | |
| SCHEMBL7273181 | 0.84 | ACE (0.50) | ACEDPP4DPP8RENACE2 | |
| SCHEMBL7264396 | 0.84 | KDM4E (0.51) | ACEDPP4DPP8RENPREP | |
| SCHEMBL7271905 | 0.83 | ACE (0.49) | ACEDPP4DPP8RENACE2 | |
| SCHEMBL7273358 | 0.83 | ACE (0.49) | ACEDPP4DPP8RENACE2 | |
| SCHEMBL7271844 | 0.82 | PRCP (0.53) | ACEDPP4DPP8RENACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931139-A | Tripeptides having an antidepressive and prolactin-releasing action | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |