Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271897 | 0.90 | ACE (0.53) | ACERENPREPACE2CYP3A4 | |
| SCHEMBL7523931 | 0.89 | ACE (0.52) | ACERENPREPDPP4DPP8 | |
| SCHEMBL7264396 | 0.87 | KDM4E (0.51) | ACERENPREPTSHRALDH1A1 | |
| SCHEMBL7273358 | 0.85 | ACE (0.49) | ACERENPREPACE2CYP3A4 | |
| SCHEMBL7271905 | 0.85 | ACE (0.49) | ACERENPREPACE2TSHR | |
| SCHEMBL7271844 | 0.85 | PRCP (0.53) | ACERENPREPACE2CYP3A4 | |
| SCHEMBL11794997 | 0.85 | ACE (0.48) | ACERENPREPACE2CYP3A4 | |
| SCHEMBL11791864 | 0.84 | ACE (0.49) | ACERENPREPACE2CYP3A4 | |
| SCHEMBL11585814 | 0.83 | ACE (0.49) | ACERENPREPCYP3A4TSHR | |
| SCHEMBL29566322 | 0.80 | CMA1 (0.53) | ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123444-A1 | 4-Substituted-2-azetidinone compound, process of producing the compounds, and medicaments containing the compounds | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |